VIP (Vasoactive Intestinal Peptide) Peptide

For Research Use Only. Not for Human Use.

Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid neuropeptide widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter and hormone. It binds to VPAC1/VPAC2 receptors to produce potent vasodilation, smooth muscle relaxation, and stimulation of secretion (e.g., intestinal fluid and pancreatic bicarbonate). First isolated in 1970 from porcine intestine, it is a key regulator of circadian rhythms, GI function, and immune modulation. This research-grade lyophilized powder is synthesized under strict quality controls and includes full analytical documentation, making it ideal for gastroenterology, neurology, and pulmonary research.

Key Scientific Features

• High-purity VIP (≥99% by HPLC/MS, acetate salt form)
• Verified 28-amino-acid sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
• Lyophilized formulation for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
• Manufactured in GMP-aligned, ISO-compliant facilities
• Ideal for VPAC receptor signaling, smooth muscle relaxation, and secretion studies

Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)

• Potent vasodilator and smooth muscle relaxant studied in receptor signaling models
• Stimulates intestinal and pancreatic secretion pathways and inhibits gastric acid secretion in vitro
• Exhibits anti-apoptotic and anti-inflammatory properties investigated in neurological research models
• Modulates circadian rhythm signaling and immune responses, including reduction of pro-inflammatory cytokines in research settings
• Short half-life (~2 minutes) makes it ideal for acute signaling studies

Why Researchers Choose Nationwide Peptides VIP

• Exact human sequence used in major neuroendocrine studies
• Transparent analytical data (HPLC >99%, MS confirmation)
• Trusted by gastroenterology, neurology, and pulmonary research laboratories
• Competitive research pricing with bulk options